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List of publications in medicine
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List of publications in medicine

This is a list of important publications in medicine, organized by field.

There are some reasons why a particular publication might be regarded as important:

Table of contents
1 Foundations
2 Recent studies
3 See also


De Materia Medica

Description: The five volume book De Materia Medica that was a precursor to all modern pharmacopeias. In fact it remained in use until about CE 1600. All that was written was a mere commentary on Dioscorides' work with minor additions from Arabian and Indian sources.

Importance: Topic creator, Breakthrough, Impact

Recent studies

Mortality in relation to smoking: 50 years' observation on male British doctors

Description: This is the
British doctors study. A prospective clinical trial which has been running from 1951 to 2001, and in 1956 provided convincing statistical proof that tobacco smoking increased the risk of lung cancer.

Importance: Impact

Randomized trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study

Description: The Scandinavian Simvastatin Survival Study (also known under the abbreviation 4S) is a multicenter clinical trial that was performed in 1990s in Scandinavia.
The objective of the study was to assess effect of cholesterol-lowering drug called simvastatin on mortality and morbidity in group of 4444 patients with coronary heart disease, aged between 35 and 70 years.
The patients presented with moderate hypercholesterolemia between 5.5 and 8.0 mmol/l.

The results of the trial showed that treatment of patients with simvastatin patients suffering from coronary heart disease had lowering effect on mortality and morbidity.

Importance: Impact

Heart Protection Study

Description: The Heart Protection Study is a large randomized controlled trial by the Medical Research Council (MRC) in the United Kingdom. It studies the use of statin (simvastatin 40 mg) medication and vitamin supplementation (vitamin E, vitamin C and beta carotene) in patients that are at risk for cardiovascular disease.

Importance: Impact

See also